Medvedev N Iu, Shastina G V
Arkh Patol. 1978;40(5):32-6.
Morphometric, histological, and immunofluorescent studies were carried out with adrenal glands of 14 infants dying with generalized adenovirus infection sometimes concurrent with other acute viral respiratory diseases. Nonspecific changes were found: edema of the capsule and stroma, discomplexation of the trabeculae, circulatory disorders, delipoidization, an increase in the content of DNA and RNA in cells of the definitive cortex, resorption of the elements of the fetal cortex. The pattern of changes of morphometric values attests to increased functional activity of the adrenal cortex. The intensity of the observed changes was directly related to the duration of the disease. The results of clinico-morphological analysis confirm the importance of adrenal insufficiency in tanatogenesis in generalized adenovirus infection. In 10 cases epithelial and endothelial cells of the definitive cortex were found to have specific lesions, the so-called adenovirus cells.
对14例死于全身性腺病毒感染（有时并发其他急性病毒性呼吸道疾病）的婴儿的肾上腺进行了形态测量、组织学和免疫荧光研究。发现了非特异性变化：包膜和间质水肿、小梁结构紊乱、循环障碍、脂质缺失、成熟皮质细胞中DNA和RNA含量增加、胎儿皮质成分吸收。形态测量值的变化模式证明肾上腺皮质功能活性增强。观察到的变化强度与疾病持续时间直接相关。临床形态学分析结果证实肾上腺功能不全在全身性腺病毒感染死亡发生过程中的重要性。在10例中，发现成熟皮质的上皮细胞和内皮细胞有特异性病变，即所谓的腺病毒细胞。
