Szekessy D P, Bamberg C, Blechschmidt C, Kaindl A M, Stoltenburg-Didinger G
Department of Neonatology, Charité - Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.
Clin Neuropathol. 2010 Nov-Dec;29(6):365-71. doi: 10.5414/npp29365.
Focal and symmetric necrotic lesions of the brainstem are thought to result from fetal hypotension or cardiac arrest in the perinatal period and thus occur in the course of postnatal intensive care rather than in utero. Here, we report for the first time on brainstem necrosis in a preterm stillborn demonstrating that brainstem necrosis occurs already in utero. The preterm stillborn of 28 weeks gestation of a mother that suffered from HELLP-syndrome was severely affected by a fetal hydrops with bilateral pleural effusions and lung hypoplasia. Bilateral tegmental brainstem necrosis and thalamic lesions were detected.
脑干局灶性和对称性坏死性病变被认为是围生期胎儿低血压或心脏骤停所致，因此发生在出生后重症监护期间而非子宫内。在此，我们首次报告了一例早产死产儿的脑干坏死，证明脑干坏死在子宫内就已发生。一名患有HELLP综合征母亲的28周妊娠早产死产儿受到严重影响，出现胎儿水肿、双侧胸腔积液和肺发育不全。检测到双侧脑干被盖坏死和丘脑病变。
