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[2型糖尿病的当前临床实践指南:应如何在初级保健中应用?]

[Current clinical practice guidelines in type 2 diabetes: how should they be applied in primary care?].

作者信息

Navarro Pérez Jorge, Adam Alejandro Navarro, Beltrán Domingo Orozco, Guillén Vicente Gil, Munuera Concepción Carratalá

机构信息

Departamento de Medicina, Universitat de València, València, España.

出版信息

Aten Primaria. 2010 Sep;42 Suppl 1(Suppl 1):9-15. doi: 10.1016/S0212-6567(10)70003-2.

Abstract

Clinical practice guidelines should be drawn up with systematic methodology based on the best available evidence. Recommendations should be based on evaluation of the overall quality of the evidence and grading of the strength of recommendations. Consensus documents combine a review of the evidence with expert opinion in an attempt to reach some agreement in areas of uncertainty due to the lack of conclusive proof. The debate aroused by new treatments stimulates the production of documents advocating their use even when there are few long-term studies on their safety and efficacy. There are several methodologically rigorous international guidelines on diabetes (NGC, NICE, SIGN, CAD, ADA). The most recent debate has centered on the ADA-EASD treatment algorithm. In Spain, the production of clinical practice guidelines with analysis of the evidence and grading of recommendations remains scarce, although the most recent published guidelines show greater rigor. More common is the drafting of consensus documents by scientific societies with the aim of combining external evidence with experience and reflection. In Spain there are also organisms (such as GuíaSalud or Fisterra) that facilitate free access to guidelines drawn up by Spanish groups.

摘要

临床实践指南应以基于现有最佳证据的系统方法制定。建议应基于对证据总体质量的评估以及推荐强度的分级。共识文件将证据审查与专家意见相结合,试图在因缺乏确凿证据而存在不确定性的领域达成某种共识。新疗法引发的争论促使人们撰写主张使用这些疗法的文件,即便对其安全性和有效性的长期研究很少。有若干关于糖尿病的方法学严谨的国际指南(美国国立指南库、英国国家卫生与临床优化研究所、苏格兰校际指南网络、加拿大安大略省临床评价科学研究所、美国糖尿病协会)。最近的争论集中在美国糖尿病协会 - 欧洲糖尿病研究协会的治疗算法上。在西班牙,尽管最近发布的指南显示出更高的严谨性,但对证据进行分析并对推荐进行分级的临床实践指南的制定仍然很少。更常见的是科学协会起草共识文件,目的是将外部证据与经验及思考相结合。在西班牙也有一些机构(如GuíaSalud或Fisterra),它们便于免费获取西班牙团体制定的指南。

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