Department of Psychiatry, University of California-San Francisco School of Medicine, San Francisco, CA, USA.
Am J Obstet Gynecol. 2011 Feb;204(2):122.e1-6. doi: 10.1016/j.ajog.2010.09.029. Epub 2010 Nov 11.
The objective of the study was to characterize the backgrounds of women who have repeat abortions.
In a cross-sectional study of 259 women (mean age, 35.2 ± 5.6 years), the relation between adverse experiences in childhood and risk of having 2 or more abortions vs 0 or 1 abortion was examined. Self-reported adverse events occurring between the ages of 0 and 12 years were summed.
Independent of confounding factors, women who experienced more abuse, personal safety, and total adverse events in childhood were more likely to have 2 or more abortions vs 0 abortions (odds ratio [OR], 2.56; 95% confidence interval [CI], 1.15-5.71; OR, 2.74; 95% CI, 1.29-5.82; and OR, 1.59; 95% CI, 1.21-2.09, respectively) and vs 1 abortion (OR, 5.83; 95% CI, 1.71-19.89; OR, 2.23; 95% CI, 1.03-4.81; and OR, 1.37; 95% CI, 1.04-1.81, respectively). Women who experienced more family disruption events in childhood were more likely to have 2 or more abortions vs 0 abortions (OR, 1.75; 95% CI, 1.14-2.69) but not vs 1 abortion (OR, 1.16; 95% CI, 0.79-1.70).
Women who have repeat abortions are more likely to have experienced childhood adversity than those having 0 or 1 abortion.
本研究旨在描述多次堕胎女性的背景特征。
在一项对 259 名女性（平均年龄 35.2±5.6 岁）的横断面研究中，研究了儿童时期不良经历与发生 2 次或 2 次以上流产与发生 0 次或 1 次流产的风险之间的关系。报告了 0-12 岁期间发生的自我报告不良事件，并将其进行了汇总。
在排除混杂因素后，儿童时期经历更多虐待、人身安全和总不良事件的女性发生 2 次或 2 次以上流产的可能性高于发生 0 次流产的女性（比值比[OR]，2.56；95%置信区间[CI]，1.15-5.71；OR，2.74；95%CI，1.29-5.82；OR，1.59；95%CI，1.21-2.09），也高于发生 1 次流产的女性（OR，5.83；95%CI，1.71-19.89；OR，2.23；95%CI，1.03-4.81；OR，1.37；95%CI，1.04-1.81）。儿童时期经历更多家庭破裂事件的女性发生 2 次或 2 次以上流产的可能性高于发生 0 次流产（OR，1.75；95%CI，1.14-2.69），但与发生 1 次流产的可能性没有差异（OR，1.16；95%CI，0.79-1.70）。
与发生 0 次或 1 次流产的女性相比，多次堕胎的女性更有可能在儿童时期经历过逆境。
