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类似于卵巢性索-间质肿瘤的子宫肿瘤:同时性类似于卵巢性索-间质肿瘤和卵巢性索肿瘤的子宫肿瘤。

Uterine tumors resembling ovarian sex cord-stromal tumors: synchronous uterine tumors resembling ovarian sex cord-stromal tumors and ovarian sex cord tumor.

机构信息

Department of Pathology, Hacettepe University, 06100 Ankara, Turkey.

出版信息

Ann Diagn Pathol. 2010 Dec;14(6):432-7. doi: 10.1016/j.anndiagpath.2010.07.001.

Abstract

Uterine tumors resembling ovarian sex cord-stromal tumors (UTROSCTs) are very rare. In this article, we present 3 cases that manifest classical histomorphological features alongside diverse immunohistochemical findings. As a distinctive finding, one of the patients had UTROSCT in the uterus and an ovarian sex cord tumor, called granulosa cell tumor, in the left ovary, simultaneously. Problems in diagnosing such pathologic condition generally arise because of the variable histologic picture of UTROSCT and may cause problems for general and other nongynecologic surgical pathologists. Immunohistochemically, these tumors express different markers that indicate their polyphenotypic origins.

摘要

类似于卵巢性索-间质肿瘤的子宫肿瘤(UTROSCT)非常罕见。本文报道了 3 例具有经典组织形态学特征和不同免疫组织化学表现的病例。一个特别的发现是,其中 1 例患者的子宫中存在 UTROSCT,而左侧卵巢中存在卵巢性索肿瘤,即颗粒细胞瘤。这种病理情况的诊断通常会存在问题,因为 UTROSCT 的组织学表现具有多样性,可能会给普通外科病理学家和其他非妇科外科病理学家带来问题。免疫组织化学染色显示,这些肿瘤表达不同的标志物,表明其多能性起源。

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