调强放疗联合每周顺铂治疗头颈部鳞状细胞癌后复发模式。
Patterns of relapse following definitive treatment of head and neck squamous cell cancer by intensity modulated radiotherapy and weekly cisplatin.
机构信息
Department of Oncology, Helsinki University Central Hospital, Finland.
出版信息
Radiother Oncol. 2011 Jan;98(1):34-7. doi: 10.1016/j.radonc.2010.10.015. Epub 2010 Nov 11.
PMID:21074875
Abstract
Eighty-three patients with oropharyngeal, hypopharyngeal or laryngeal cancer were treated with concomitant cisplatin 40 mg/m(2) once a week during the radiotherapy and IMRT up to a total dose of 70 Gy. The 2-year rate of local control, overall survival and disease specific survival were 84%, 82% and 89%, respectively. The corresponding 5-year Kaplan-Meier estimates were 79%, 69% and 76%.
摘要
83 例口咽、下咽或喉癌患者在放疗和调强放疗期间每周接受顺铂 40mg/m(2)联合治疗，总剂量达 70Gy。2 年局部控制率、总生存率和疾病特异性生存率分别为 84%、82%和 89%。相应的 5 年 Kaplan-Meier 估计值分别为 79%、69%和 76%。
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