Xenellis John, Mountricha Aikaterina, Maragoudakis Pavlos, Kandiloros Dimitrios, Assimakopoulos Dimitrios, Linthicum Fred J H, Nikolopoulos Thomas P
1st and 2nd Department of Otorhinolaryngology, Athens University, Athens, Greece.
Auris Nasus Larynx. 2011 Jun;38(3):325-8. doi: 10.1016/j.anl.2010.10.002. Epub 2010 Nov 12.
to analyse a large series of patients with initial diagnosis of chronic otitis media (COM) with a polypoid mass in the external ear canal (EAC).
185 consecutive patients with COM were evaluated; 75 showed a polypoid mass in the EAC.
In 65 out of the 75 (86.7%) patients, histological examination after mastoidectomy revealed cholesteatoma. In the remaining 10 (13.3%) cases, the histological diagnosis was: glomus tumor, melanoma, mucosal adenoma, fibrous dysplasia, squamous cell carcinoma, adenoma of the endolymphatic sac, encephalocele, and tuberculosis. One patient (glomus tumor) had undergone biopsy of the polypoid mass twice preoperatively and the initial histological diagnosis was "inflammatory polyp". Therefore, we examined the temporal bones with a glomus tumor diagnosis from the temporal bone collection of the House Ear Institute. In 1560 temporal bones, a glomus tympanicum was found in 6. In four cases, the tumor extended to the EAC mimicking a polyp covered by squamous epithelium.
A significant percentage of polyps in COM may be the tip of an 'iceberg'. CT-scan and MRI techniques may be helpful but not always accurate, and biopsies have certain risks. Increased clinical suspicion may limit misdiagnosis and inappropriate management.
分析大量初诊为慢性中耳炎(COM)且外耳道(EAC)有息肉样肿物的患者。
对185例连续性COM患者进行评估;其中75例EAC有息肉样肿物。
75例患者中65例(86.7%)在乳突切除术后组织学检查显示为胆脂瘤。其余10例(13.3%)病例的组织学诊断为:血管球瘤、黑色素瘤、黏膜腺瘤、骨纤维异常增殖症、鳞状细胞癌、内淋巴囊腺瘤、脑膨出和结核。1例患者(血管球瘤)术前对息肉样肿物进行了两次活检,最初的组织学诊断为“炎性息肉”。因此,我们从豪斯耳科研究所的颞骨标本中检查了诊断为血管球瘤的颞骨。在1560块颞骨中,发现6块有鼓室血管球瘤。在4例中,肿瘤延伸至EAC,类似被鳞状上皮覆盖的息肉。
COM中相当一部分息肉可能只是“冰山一角”。CT扫描和MRI技术可能有帮助,但并不总是准确,活检有一定风险。提高临床怀疑度可能会减少误诊和不恰当的处理。