Magliocca Kelly R, Vivas Esther X, Griffith Christopher C
Department of Pathology and Lab Medicine, Emory University, 550 Peachtree St. NE, Atlanta, GA, 30308, USA.
Department of Otolaryngology - Head & Neck Surgery, Emory University, 550 Peachtree St. NE, Atlanta, GA, 30308, USA.
Head Neck Pathol. 2018 Sep;12(3):328-349. doi: 10.1007/s12105-018-0952-0. Epub 2018 Aug 1.
A number of infectious, inflammatory and idiopathic lesions develop within otologic tissues that may share similar clinical and/or microscopic features. This review first provides a working classification for otitis externa, and then otitis media and includes two recently described entities, eosinophilic otitis media and otitis media with ANCA-associated vasculitis. Next, the microscopic findings of a spectrum of otopathologic conditions are described, including post-inflammatory conditions such as tympanosclerosis and aural polyps, an overview of animate aural foreign body as well as iatrogenic aural foreign body reactions. Finally, a review of fungal disease affecting the ear with a brief synopsis of Candida auris, a recently described and virulent organism, is presented.
许多感染性、炎症性和特发性病变会在耳科组织内发生,这些病变可能具有相似的临床和/或微观特征。本综述首先提供了外耳道炎的实用分类,然后是中耳炎,并包括两个最近描述的实体,即嗜酸性中耳炎和与抗中性粒细胞胞浆抗体相关血管炎的中耳炎。接下来,描述了一系列耳病理状况的微观发现,包括炎症后状况,如鼓室硬化和耳息肉,活体耳异物概述以及医源性耳异物反应。最后,对影响耳朵的真菌病进行了综述,并简要介绍了耳念珠菌,一种最近描述的高致病性生物体。