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台湾一家医疗中心心脏手术后手术部位感染的结果和相关风险因素。

Outcome and risk factors associated with surgical site infections after cardiac surgery in a Taiwan medical center.

机构信息

Department of Nursing, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

出版信息

J Microbiol Immunol Infect. 2010 Oct;43(5):378-85. doi: 10.1016/S1684-1182(10)60060-6.

Abstract

BACKGROUND/PURPOSE: Surgical site infection (SSI) after cardiac surgery leads to morbidity and mortality. Identifying SSI risk factors, which vary between populations, is important in preventing infection.

METHODS

A retrospective chart review of adult cases receiving cardiac surgery in a Taiwan medical center in 2004 and 2005.

RESULTS

Of the 260 cases included in the study, 169 (65.0%) received a coronary artery bypass graft, 65 (25.0%) cardiac valvular surgery and 26 (10.0%) aortic or septal defect operations. The SSI rate was 13.5%. Univariate analysis showed that chronic obstructive pulmonary disease (COPD) (p = 0.008), congestive heart failure New York Heart Association class IV (p = 0.048), longer preoperative hospital stay, preoperative nosocomial infection, higher volume of blood loss and larger packed red blood cell transfusions during the operation were significantly related to SSI. Logistic regression analysis further identified COPD, pre-operative nosocomial infection and emergency surgery as being independently associated with SSI (odds ratios of 4.96, 5.88 and 9.77, respectively). Obesity and diabetes mellitus were not associated with SSI.

CONCLUSION

COPD is an independent underlying illness associated with SSI after cardiac surgery. Minimizing preoperative hospitalization and nosocomial infection, and awareness of cases presenting with relevant risk factors, are useful in reducing SSI.

摘要

背景/目的:心脏手术后的手术部位感染(SSI)会导致发病率和死亡率。确定 SSI 风险因素对于预防感染很重要,这些因素因人群而异。

方法

对 2004 年和 2005 年在台湾一家医疗中心接受心脏手术的成年病例进行回顾性图表审查。

结果

在纳入研究的 260 例病例中,169 例(65.0%)接受了冠状动脉旁路移植术,65 例(25.0%)接受了心脏瓣膜手术,26 例(10.0%)接受了主动脉或间隔缺损手术。SSI 发生率为 13.5%。单因素分析显示,慢性阻塞性肺疾病(COPD)(p=0.008)、充血性心力衰竭纽约心脏协会(NYHA)IV 级(p=0.048)、术前住院时间延长、术前院内感染、术中失血量增加和较大的红细胞悬液输注与 SSI 显著相关。逻辑回归分析进一步确定 COPD、术前院内感染和急诊手术与 SSI 独立相关(比值比分别为 4.96、5.88 和 9.77)。肥胖和糖尿病与 SSI 无关。

结论

COPD 是心脏手术后 SSI 的独立基础疾病。尽量减少术前住院时间和院内感染,并注意有相关风险因素的病例,有助于降低 SSI。

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