Hoffmann Henry, Giger Olivier Thierry, Bubendorf Lukas, Lardinois Didier
Department of Surgery, University Hospital of Basel, Spitalstrasse 21, 4031 Basel, Switzerland.
Interact Cardiovasc Thorac Surg. 2011 Feb;12(2):306-7. doi: 10.1510/icvts.2010.252874. Epub 2010 Nov 12.
We present an unusual case of a contralateral recurrence of malignant solitary fibrous tumor of the pleura (SFTP) nine years after a complete resection. Recurrence of malignant SFTP has already been described, but is usually localized. In our case the patient underwent surgical resection for a malignant SFTP of the left upper lobe in 2000. Nine years later computed tomography (CT)-scans showed lesions that were suspicious of tumor recurrence in the right lung. Thoracoscopy, wedge-resections and pathological findings revealed four nodules of a malignant SFTP of the right middle and lower lobe, histopathologically identical to the tumor, which had been resected nine years ago. A coincidental mucinous bronchioloalveolar carcinoma of the left lower lobe was resected by thoracotomy. To our knowledge this is the first report of contralateral recurrence of a malignant SFTP years after complete resection in the literature. The possibility of a new primary tumor on the right with local metastasis could not be excluded in the clinical and histopathological examinations. Therefore, contralateral recurrence of malignant SFTP should be considered in the postoperative follow-up even years after complete resection.
我们报告一例罕见病例，一名患者在胸膜恶性孤立性纤维瘤（SFTP）完全切除九年后出现对侧复发。恶性SFTP的复发已有报道，但通常为局限性复发。在我们的病例中，患者于2000年因左上叶恶性SFTP接受了手术切除。九年后，计算机断层扫描（CT）显示右肺有可疑肿瘤复发的病变。胸腔镜检查、楔形切除术及病理检查发现右中、下叶有四个恶性SFTP结节，组织病理学与九年前切除的肿瘤相同。同时通过开胸手术切除了左下叶的黏液性细支气管肺泡癌。据我们所知，这是文献中首例完全切除多年后恶性SFTP对侧复发的报道。在临床和组织病理学检查中不能排除右侧出现新的原发性肿瘤并伴有局部转移的可能性。因此，即使在完全切除多年后的术后随访中，也应考虑恶性SFTP对侧复发的可能性。
