School of Public Health, University of California, Berkeley, California, USA.
Sex Transm Infect. 2011 Mar;87(2):162-4. doi: 10.1136/sti.2010.042986. Epub 2010 Nov 12.
To assess changes in seroadaptive behaviours among men who have sex with men (MSM) in San Francisco over the past 4 years.
461 MSM were recruited in 2008 as the second wave of the US National HIV Behavioural Surveillance (NHBS) survey in San Francisco. Participants were classified into patterns of seroadaptive behaviours based on reported sexual practices (ie, episodes of insertive and receptive anal sex), condom use, HIV serostatus and partners' serostatus for up to five partners in the preceding 6 months. The prevalence of seroadaptive behaviours was compared with the first wave of NHBS, which used identical methods in 2004.
In 2008, 33.7% of HIV-negative and 18.9% of HIV-positive MSM used condoms 100% of the time; nearly half (48.0%) of HIV-negative MSM and two-thirds (66.7%) of HIV-positive MSM had unprotected anal intercourse (UAI). Collectively, seroadaptive behaviours comprised the most common form of risk management; 40.5% of HIV-negative MSM and 51.1% of HIV-positive MSM engaged in some form of seroadaptation, the most common being 'pure serosorting' (all UAI with same serostatus partners) reported by 27.5% of HIV-negative MSM and 22.2% of HIV-positive MSM. None of these behaviours were significantly different from their corresponding measures in 2004.
Seroadaptation continues to describe the prevailing form of sexual risk management for MSM in San Francisco, suggesting that these behaviours are not novel and require careful measurement to gauge the true potential for the spread of HIV, and nuanced prevention messages to reduce risk.
评估过去 4 年旧金山男男性行为者（MSM）的血清适应行为变化。
2008 年，461 名 MSM 作为美国国家 HIV 行为监测（NHBS）调查在旧金山的第二波参与者被招募。根据报告的性行为（即插入性和接受性肛交）、 condom 使用、HIV 血清状况和前 6 个月最多 5 名性伴侣的血清状况，参与者被分为血清适应行为模式。将血清适应行为的流行率与 2004 年使用相同方法的 NHBS 第一波进行比较。
2008 年，33.7%的 HIV 阴性和 18.9%的 HIV 阳性 MSM 100%使用 condom；近一半（48.0%）的 HIV 阴性 MSM 和三分之二（66.7%）的 HIV 阳性 MSM 发生无保护肛交（UAI）。总体而言，血清适应行为是最常见的风险管理形式；40.5%的 HIV 阴性 MSM 和 51.1%的 HIV 阳性 MSM 采取某种形式的血清适应，最常见的是“纯血清分类”（与相同血清状态的伴侣发生所有 UAI），27.5%的 HIV 阴性 MSM 和 22.2%的 HIV 阳性 MSM 报告了这种行为。这些行为与 2004 年的相应措施均无显著差异。
血清适应继续描述旧金山 MSM 普遍存在的性行为风险管理形式，表明这些行为并非新颖，需要仔细测量以评估 HIV 传播的真实潜力，并提供微妙的预防信息以降低风险。
