University Hospital for Orthopaedic Surgery Lovran, Marsala Tita 1, 51415, Lovran, Croatia.
Knee Surg Sports Traumatol Arthrosc. 2011 Jun;19(6):955-9. doi: 10.1007/s00167-010-1309-8. Epub 2010 Nov 13.
As the blood loss after the total knee arthroplasty (TKA) is not only a potentially serious medical problem but also an economical concern, the purpose of the study was to investigate the effectiveness of different combinations of knee positioning and the applied wound dressings on blood saving after TKA.
A randomized controlled trial including 147 TKA-operated patients was conducted. The subjects were assigned to one of the four groups; Group 1-controls, Group 2-flexion, Group 3-flexion and compression, Group 4-compression. The main outcome measures of the study were the blood loss volumes during the procedure and in the intensive care rooms and the decreases in haemoglobin, haemotocrit and red blood cells on the first and the second postoperative day.
The MANOVA results showed no differences between the groups in any of the observed parameters. The post-hoc comparisons of the each group to the control group also revealed no influence of any of the proposed blood saving techniques on the actual blood loss.
No significant differences among the four proposed blood saving methods were determined.
全膝关节置换术（TKA）后的失血不仅是一个潜在的严重医学问题，也是一个经济问题，因此本研究旨在探讨膝关节定位和应用的不同伤口敷料组合对 TKA 后血液保存的效果。
进行了一项包括 147 例 TKA 手术患者的随机对照试验。将受试者分为四组中的一组；第 1 组为对照组，第 2 组为膝关节弯曲组，第 3 组为膝关节弯曲和压缩组，第 4 组为压缩组。本研究的主要观察指标为手术过程中和重症监护室中的失血量，以及术后第 1 天和第 2 天血红蛋白、血细胞比容和红细胞的下降量。
MANOVA 结果显示，在任何观察到的参数中，组间均无差异。对每组与对照组的事后比较也表明，任何一种拟议的血液保存技术都不会对实际失血量产生影响。
四种拟议的血液保存方法之间没有显著差异。
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