Morioka Shigemi, Otabe Osamu, Uehara Hisaki, Yokoi Kentaro, Ohmizono Yoshikazu, Ishimaru Yosuke, Morimoto Masafumi, Hosoi Hajime
Department of Pediatrics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto.
No To Hattatsu. 2010 Nov;42(6):449-53.
We report a 2-year-old girl who demonstrated "benign convulsions with gastroenteritis (CwG)" with transient splenial lesions twice during the winter. The first episode was associated with noro-virus and the second with rota-virus. During each episode, seizures occurred in clusters without clinical signs of dehydration, hypoglycemia, electrolyte derangement or cerebrospinal fluid abnormalities, and her consciousness was clear during the interictal period. Those findings were consistent with CwG. As transient splenial lesions were not accompanied by any neurological abnormalities other than seizures, she was not diagnosed as having encephalopathy, but as having CwG. Diffusion-weighted magnetic resonance imaging of the brain demonstrated hyperintense lesions in the splenium of the corpus callosum, which disappeared within a week. We speculate that CwG is likely to lead to transient splenial lesions.
我们报告一名2岁女童，在冬季两次出现伴有短暂性胼胝体压部病变的“伴肠胃炎的良性惊厥（CwG）”。第一次发作与诺如病毒有关，第二次与轮状病毒有关。在每次发作期间，惊厥成簇发生，无脱水、低血糖、电解质紊乱或脑脊液异常的临床体征，且在发作间期意识清醒。这些发现与CwG一致。由于短暂性胼胝体压部病变除惊厥外未伴有任何神经异常，她未被诊断为脑病，而是被诊断为CwG。脑部弥散加权磁共振成像显示胼胝体压部有高信号病变，一周内消失。我们推测CwG可能导致短暂性胼胝体压部病变。
