使用胸腺嘧啶修饰的金纳米颗粒对Hg2+进行高选择性的视觉检测。

Visual detection of Hg2+ with high selectivity using thymine modified gold nanoparticles.

作者信息

Liu Xiangjun, Cheng Xiaohong, Bing Tao, Fang Canliang, Shangguan Dihua

机构信息

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China.

出版信息

Anal Sci. 2010;26(11):1169-72. doi: 10.2116/analsci.26.1169.

DOI:10.2116/analsci.26.1169

PMID:21079347

Abstract

Here, we describe a colorimetric sensor for detecting Hg(2+) in aqueous media, which is simply constructed by the self-assembly of thymine acetamidoethanethiol (T-SH) on gold nanoparticles (AuNPs). Based on the specific interaction of Hg(2+) with two thymines (T), the T-SH modified AuNPs can be induced to aggregate through the formation of a stable T-Hg-T complex in the presence of Hg(2+), resulting in a color change from red to blue-gray. As low as 0.5 µM of Hg(2+) can be easily monitored by the naked eye using this sensor. Other metal ions, including Zn(2+), Cd(2+), Pb(2+), Ni(2+), Cu(2+), Co(2+), Mn(2+), Ba(2+), Fe(2+), Ca(2+), Mg(2+), Al(3+), and Fe(3+), could not cause any response, even at concentrations 100-fold higher than Hg(2+). The high selectivity, high stability and easy operation enable this sensor suitable for the rapid on-site detection of Hg(2+) pollution.

摘要

在此，我们描述了一种用于检测水介质中Hg(2+)的比色传感器，它通过胸腺嘧啶乙酰氨基乙硫醇（T-SH）在金纳米颗粒（AuNPs）上的自组装简单构建而成。基于Hg(2+)与两个胸腺嘧啶（T）的特异性相互作用，在Hg(2+)存在的情况下，T-SH修饰的AuNPs可通过形成稳定的T-Hg-T络合物而被诱导聚集，导致颜色从红色变为蓝灰色。使用该传感器，肉眼可轻松监测低至0.5 μM的Hg(2+)。其他金属离子，包括Zn(2+)、Cd(2+)、Pb(2+)、Ni(2+)、Cu(2+)、Co(2+)、Mn(2+)、Ba(2+)、Fe(2+)、Ca(2+)、Mg(2+)、Al(3+)和Fe(3+)，即使浓度比Hg(2+)高100倍，也不会引起任何响应。高选择性、高稳定性和易于操作使得该传感器适用于Hg(2+)污染的快速现场检测。