Kaprana Antigoni E, Chimona Theognosia S, Papadakis Chariton E, Velegrakis Stylianos G, Vardiambasis Ioannis O, Adamidis Georgios, Velegrakis George A
ENT Department, Chania General Hospital, Mournies, Greece.
Audiol Neurootol. 2011;16(4):270-6. doi: 10.1159/000321337. Epub 2010 Nov 16.
The objective of the present study was to investigate the possible electrophysiological time-related changes in auditory pathway during mobile phone electromagnetic field exposure. Thirty healthy rabbits were enrolled in an experimental study of exposure to GSM-900 radiation for 60 min and auditory brainstem responses (ABRs) were recorded at regular time-intervals during exposure. The study subjects were radiated via an adjustable power and frequency radio transmitter for GSM-900 mobile phone emission simulation, designed and manufactured according to the needs of the experiment. The mean absolute latency of waves III-V showed a statistically significant delay (p < 0.05) after 60, 45 and 15 min of exposure to electromagnetic radiation of 900 MHz, respectively. Interwave latency I-III was found to be prolonged after 60 min of radiation exposure in correspondence to wave III absolute latency delay. Interwave latencies I-V and III-V were found with a statistically significant delay (p < 0.05) after 30 min of radiation. No statistically significant delay was found for the same ABR parameters in recordings from the ear contralateral to the radiation source at 60 min radiation exposure compared with baseline ABR. The ABR measurements returned to baseline recordings 24 h after the exposure to electromagnetic radiation of 900 MHz. The prolongation of interval latencies I-V and III-V indicates that exposure to electromagnetic fields emitted by mobile phone can affect the normal electrophysiological activity of the auditory system, and these findings fit the pattern of general responses to a stressor.
本研究的目的是调查在手机电磁场暴露期间听觉通路可能存在的与时间相关的电生理变化。30只健康兔子参与了一项暴露于GSM - 900辐射60分钟的实验研究，并在暴露期间按固定时间间隔记录听觉脑干反应（ABR）。研究对象通过一个根据实验需求设计和制造的可调功率和频率的无线电发射器进行辐射，以模拟GSM - 900手机的发射。在分别暴露于900 MHz电磁辐射60分钟、45分钟和15分钟后，波III - V的平均绝对潜伏期显示出具有统计学意义的延迟（p < 0.05）。在辐射暴露60分钟后，发现波间潜伏期I - III与波III绝对潜伏期延迟一致地延长。在辐射30分钟后，发现波间潜伏期I - V和III - V具有统计学意义的延迟（p < 0.05）。在辐射暴露60分钟时，与基线ABR相比，来自辐射源对侧耳的记录中相同ABR参数未发现具有统计学意义的延迟。在暴露于900 MHz电磁辐射24小时后，ABR测量结果恢复到基线记录。波间潜伏期I - V和III - V的延长表明暴露于手机发出的电磁场会影响听觉系统的正常电生理活动，并且这些发现符合对应激源的一般反应模式。
