Han S N, Van Calsteren K, Heyns L, Mhallem Gziri M, Amant F
Leuven Cancer Institute, Gynaecological Oncology, UZ Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium.
Minerva Ginecol. 2010 Dec;62(6):585-97.
Breast cancer during pregnancy is relatively uncommon. However, the incidence is expected to increase as more women delay childbearing. A challenging situation emerges for all persons involved ‑ patient, family and medical care workers ‑ since two lives are at risk with contradicting priorities. Breast cancer treatment is possible during pregnancy. The treatment plan needs to adhere as closely as possible to standardised protocols for nonpregnant patients, with some considerations to minimize fetal exposure and risks. This concerns mainly limiting radiation exposure and timing of chemotherapy to start in the second trimester. The prognosis of pregnant women does not seem to differ from that of nonpregnant patients when matched for age and stage of the disease. This literature review concentrates on the diagnosis, treatment and outcome of patients diagnosed with breast cancer during pregnancy.
妊娠期乳腺癌相对少见。然而，随着越来越多的女性推迟生育，其发病率预计将会上升。对于所有相关人员——患者、家属及医护人员而言，一种具有挑战性的情况出现了，因为两条生命面临危险且存在相互矛盾的优先事项。妊娠期乳腺癌是可以治疗的。治疗方案需要尽可能遵循针对非妊娠患者的标准化方案，同时要进行一些考量以尽量减少胎儿接触及风险。这主要涉及限制辐射暴露以及将化疗时间安排在孕中期开始。在年龄和疾病分期相匹配时，孕妇的预后似乎与非妊娠患者并无差异。这篇文献综述聚焦于妊娠期被诊断为乳腺癌的患者的诊断、治疗及预后情况。
