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挪威多发性硬化症的成本。

The cost of multiple sclerosis in Norway.

机构信息

Department of Finance and Management Science, Norwegian School of Economics and Business Administration, 5021 Bergen, Norway.

出版信息

Eur J Health Econ. 2012 Feb;13(1):81-91. doi: 10.1007/s10198-010-0286-7. Epub 2010 Nov 16.

Abstract

Health economic aspects have been increasingly important during introduction of new treatments for multiple sclerosis. As a partial response for Norway, a cost-of-illness study was carried out to estimate the yearly cost of the illness to society and relate costs and patients' quality of life to illness severity. Estimated cost to society was Euro 439 million in 2002 exclusive of the cost of reduced quality of life. The cost per patient was close to Euro 65,000. Account taken of methodological differences, the results compare to results for Sweden, Norway's closest neighboring country. The illness reduced patients' quality of life with 0.26. More patients were early retired because of their MS in Norway than in any of nine other European countries comprised by a recent European study, illustrating a liberal practice in Norway. The Norwegian cost of unpaid assistance was almost identical to the Swedish cost that was the lowest found across the countries in the European study. When related to illness severity, the cost per patient increased, and the patients' experienced quality of life decreased with increasing EDSS levels in line with what has been found for other countries. Cost-of-MS studies have been carried out for a number of countries. Together they contribute to our understanding of the economic consequences of multiple sclerosis and, if their results are related to illness severity, also provide valuable information for further economic analyses of treatment and medication. Our study adds to this.

摘要

在引入多发性硬化症的新疗法时,健康经济学方面变得越来越重要。作为挪威的部分回应,进行了一项疾病成本研究,以估算该病给社会带来的年度成本,并将成本和患者的生活质量与疾病严重程度联系起来。2002 年,不包括生活质量降低的成本,社会估计成本为 4.39 亿欧元。每位患者的成本接近 65000 欧元。考虑到方法上的差异,结果与挪威最近邻国瑞典的结果相比较。该疾病使患者的生活质量降低了 0.26。与欧洲最近的一项研究涵盖的九个其他欧洲国家相比,挪威有更多的患者因多发性硬化症而提前退休,这说明了挪威的宽松做法。挪威的无薪援助成本几乎与瑞典的成本相同,而瑞典的成本是欧洲研究国家中最低的。当与疾病严重程度相关时,每位患者的成本增加,并且患者的生活质量随着 EDSS 水平的升高而降低,这与其他国家的发现一致。已经为多个国家进行了多发性硬化症成本研究。它们共同有助于我们了解多发性硬化症的经济后果,如果将其结果与疾病严重程度相关,则还为进一步对治疗和药物进行经济分析提供了有价值的信息。我们的研究对此有所补充。

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