Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.
Curr Cardiol Rep. 2011 Feb;13(1):57-66. doi: 10.1007/s11886-010-0152-3.
Advancements in computed tomography (CT) technology have revolutionized clinical practice, particularly regarding the noninvasive assessment of coronary artery disease (CAD). The versatility of cardiac CT has rendered multiple applications including assessment of cardiac structure and function, myocardial viability, and coronary anatomy. The merits of cardiac computed tomography angiography (CTA) have been proven for the detection, and particularly the exclusion, of CAD. However, CTA becomes limited in the presence of significant CAD. Its inability to consistently identify lesion-associated ischemia may necessitate additional radionuclide myocardial perfusion imaging. Myocardial computed tomography perfusion imaging (CTP) has emerged as a useful and convenient method to immediately assess myocardial ischemia. In this review, we discuss the current state of CTP including available technology, its performance to date from current literature, and future challenges to this field.
计算机断层扫描（CT）技术的进步彻底改变了临床实践，尤其是在非侵入性评估冠状动脉疾病（CAD）方面。心脏 CT 的多功能性使其具有多种应用，包括评估心脏结构和功能、心肌活力以及冠状动脉解剖结构。心脏 CT 血管造影（CTA）在 CAD 的检测，特别是排除方面的优势已得到证实。然而，当 CAD 严重时，CTA 就会受到限制。它不能始终识别与病变相关的缺血，可能需要额外的放射性核素心肌灌注成像。心肌 CT 灌注成像（CTP）已成为一种有用且方便的方法，可立即评估心肌缺血。在这篇综述中，我们讨论了 CTP 的现状，包括现有的技术、目前文献中的表现以及该领域未来的挑战。
