Department of Chemistry, University of Liverpool, Crown Street, Liverpool L697ZD, UK.
Macromol Biosci. 2011 Feb 11;11(2):160-73. doi: 10.1002/mabi.201000316. Epub 2010 Nov 15.
Dipeptide and tripeptide conjugates are receiving significant current interest as LMWG, driven by the accessibility of these materials, their relatively low cost and also the large number of examples that successfully form hydrogels. Their behaviour can easily modified by changes in the amino acids or the aromatic end groups chosen. The assembly process has been relatively well described for a small subset of these gelators, giving a good idea of the behaviour of these molecules and allowing an understanding of the conditions under which assembly will occur. Here, we critically review the literature in this area and consider the importance of gelator choice and method of assembly on the outcome of the gelation. We also discuss the applications of these hydrogels.
二肽和三肽缀合物作为 LMWG 受到了当前的广泛关注，这得益于这些材料的易得性、相对较低的成本以及大量成功形成水凝胶的实例。通过改变所选氨基酸或芳基末端基团，很容易改变它们的行为。对于这些凝胶剂中的一小部分，已经对其组装过程进行了相对较好的描述，这使我们对这些分子的行为有了很好的了解，并使我们能够理解发生组装的条件。在这里，我们批判性地回顾了这一领域的文献，并考虑了凝胶剂选择和组装方法对凝胶形成结果的重要性。我们还讨论了这些水凝胶的应用。
