Division of Hematology, Oncology & Transplantation, University of Minnesota, MN, USA.
Expert Rev Hematol. 2009 Apr;2(2):173-82. doi: 10.1586/ehm.09.7.
The incidence of non-Hodgkin's lymphoma (NHL) is increasing among all age groups, with a median age at diagnosis of 67 years. With the increase in the geriatric population, there is a need for the development and validation of treatment strategies for NHL for these patients. Therapy in elderly patients is affected by multiple factors, especially comorbidities. Over the past decade, some treatment trials have included older patients. The disease incidence, characteristics and treatment approaches for both follicular and diffuse aggressive NHL histologies in elderly patients are reviewed, as well as the impact of aging on the care of these patients.
非霍奇金淋巴瘤（NHL）的发病率在所有年龄段都在增加，中位诊断年龄为 67 岁。随着老年人口的增加，需要为这些患者开发和验证 NHL 的治疗策略。老年患者的治疗受到多种因素的影响，特别是合并症。在过去的十年中，一些治疗试验已经纳入了老年患者。本文回顾了老年患者滤泡性和弥漫性侵袭性 NHL 组织学的疾病发生率、特征和治疗方法，以及衰老对这些患者护理的影响。
