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综述文章:向患者解释炎症性肠病治疗的风险。

Review article: explaining risks of inflammatory bowel disease therapy to patients.

机构信息

Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.

出版信息

Aliment Pharmacol Ther. 2011 Jan;33(1):23-32. doi: 10.1111/j.1365-2036.2010.04489.x. Epub 2010 Oct 26.

DOI:10.1111/j.1365-2036.2010.04489.x
PMID:21083583
Abstract

BACKGROUND

Medical treatment for inflammatory bowel disease (IBD) has advanced significantly over the past decade, but it is important to communicate effectively the balance of benefits and risks of therapy to patients to facilitate informed medical decisions.

AIM

To review the available data describing the risk of side effects of IBD medications and to describe effective methods for communicating risk.

METHODS

To identify relevant articles for this review, a PubMed search was conducted using relevant key words and phrases. In addition, reference lists from identified manuscripts were searched and recent abstracts from National meetings were reviewed.

RESULTS

The steroid-sparing medications used for the treatment of IBD all carry risks of both common and rare adverse events. Trade-offs need to be made between the risks of these medications vs. the risks of poorly treated disease and corticosteroids. There has been significant research on how best to present risk data to patients, which is summarized in this review.

CONCLUSIONS

To ensure that our patients understand their choices and feel comfortable with their treatment, we need to communicate risk data to patients clearly. Patients comprehend absolute numbers better than relative risk, and when available, pictorial representations of data are preferred over solely presenting numerical outcomes.

摘要

背景

在过去的十年中,炎症性肠病(IBD)的治疗取得了重大进展,但向患者有效传达治疗的益处和风险的平衡对于促进知情的医疗决策非常重要。

目的

回顾描述 IBD 药物副作用风险的现有数据,并描述有效沟通风险的方法。

方法

为了确定本次综述的相关文章,使用相关的关键词和短语进行了 PubMed 搜索。此外,还搜索了已确定的手稿的参考文献,并审查了来自国家会议的最新摘要。

结果

用于治疗 IBD 的类固醇节省药物都存在常见和罕见不良事件的风险。需要在这些药物的风险与治疗不佳的疾病和皮质类固醇的风险之间进行权衡。已经对如何最好地向患者呈现风险数据进行了大量研究,本综述对此进行了总结。

结论

为了确保我们的患者了解他们的选择并对他们的治疗感到满意,我们需要向患者清楚地传达风险数据。患者更能理解绝对数字,而不是相对风险,并且在有条件的情况下,数据的图像表示优于仅呈现数值结果。

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