Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Clin Transplant. 2011 May-Jun;25(3):337-44. doi: 10.1111/j.1399-0012.2010.01351.x. Epub 2010 Nov 17.
As the average age of a renal transplant candidate increases, the challenge of managing recipient vascular disease affecting renal allograft function will become more common. Pre-operative screening can reveal the presence of atheromatous disease that could adversely affect allograft transplantation and function, but parameters for successful screening have not been established. Treatment options include pre-operative revascularization, concurrent therapy or delayed revascularization. Endovascular therapies have burgeoned but surgical correction is still required for some of the more complex, long-segment lesions. Potential surgical interventions range from endarterectomy to aorto-iliac bypasses. We present a case of immediate post-operative revascularization using a femoro-femoral bypass to salvage a renal allograft. The literature is reviewed to assess best practices for detecting peripheral vascular disease in renal transplant candidates and subsequent management options.
随着肾移植候选人的平均年龄增加,管理影响肾移植功能的受者血管疾病的挑战将变得更加普遍。术前筛查可以发现可能对移植物移植和功能产生不利影响的动脉粥样硬化疾病,但尚未确定成功筛查的参数。治疗选择包括术前血运重建、同时治疗或延迟血运重建。血管内治疗已经蓬勃发展,但对于一些更复杂的长节段病变,仍需要手术矫正。潜在的手术干预措施包括内膜切除术至主动脉-髂动脉旁路术。我们报告了一例使用股-股旁路术进行术后即刻血运重建以抢救肾移植的病例。回顾文献评估检测肾移植候选人外周血管疾病的最佳实践和随后的管理选择。