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活体供肝右半肝切除与左外叶切除有区别吗?切得越多,损伤越大?

Is there any difference between right hepatectomy and left lateral sectionectomy for living donors? as much you cut, as much you hurt?

机构信息

Liver Transplantation Unit, Bonsucesso Federal Hospital - Health Ministry, Rio de Janeiro, Brazil.

出版信息

HPB (Oxford). 2010 Dec;12(10):684-7. doi: 10.1111/j.1477-2574.2010.00233.x.

Abstract

BACKGROUND

The worldwide rising demand for cadaveric donors in liver transplantation is an important incentive for the development of alternative transplantation options, such as living donors. A precise evaluation of surgical complications is, therefore, considered to be an important issue in this setting.

AIM

Present a retrospective analysis of 126 living donors hepatectomies undertaken at our centre.

METHODS

From December 2002 to August 2009, 126 living donors were submitted to hepatectomy. Donors' complications were stratified according to Clavien's scoring system to compare the morbidity of right hepatectomy (RH) (Group 1) and left lateral sectionectomy (LLS) (Group 2).

RESULTS

Thirty-nine complications were observed in 35 patients. Sixty LLS, 3 left (LH) and 63 RH were performed. The complications were classified as: Clavien grade 1-11 (28.2%), grade 2-12 (30.7%), grade 3A-13 (33.3%), grade 3B-2 (5.1%) and grade 4A-1 (2.5%). When Group 1 (63 patients) and Group 2 (60 patients) were compared, there was no significant difference between the number of complications: 20 (31%) and 14 (23%), respectively (P > 0.3).

CONCLUSIONS

Hepatectomy for living donor liver transplantation (LDLT) was a safe procedure, regardless of the type of liver resection undertaken. We found no difference in morbidity between RH and LLS, which suggests that complications may occur despite the amount of liver retrieved.

摘要

背景

在肝移植中,全球对尸体供体的需求不断增加,这是开发替代移植选择(如活体供体)的重要动力。因此,准确评估手术并发症被认为是这方面的一个重要问题。

目的

分析本中心 126 例活体供肝切除术的回顾性研究。

方法

2002 年 12 月至 2009 年 8 月,126 例活体供者接受肝切除术。根据 Clavien 评分系统对供者的并发症进行分层,比较右半肝切除术(RH)(第 1 组)和左外叶切除术(LLS)(第 2 组)的发病率。

结果

35 例患者出现 39 种并发症。行 63 例 RH、6 例 LH 和 60 例 LLS。并发症分为:Clavien 1-11 级(28.2%)、2-12 级(30.7%)、3A-13 级(33.3%)、3B-2 级(5.1%)和 4A-1 级(2.5%)。当第 1 组(63 例)和第 2 组(60 例)比较时,并发症的数量无显著差异:分别为 20 例(31%)和 14 例(23%)(P>0.3)。

结论

活体供肝肝移植(LDLT)肝切除术是一种安全的手术,与所进行的肝切除类型无关。我们发现 RH 和 LLS 的发病率无差异,这表明尽管肝切除量不同,仍可能发生并发症。

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