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[帕金森病患者流涎的治疗]

[Treatment of drooling in patients with parkinsonism].

作者信息

van Onna Marieke, van Laar Teus

机构信息

Universitair Medisch Centrum Groningen, afd. Neurologie, Groningen, The Netherlands.

出版信息

Ned Tijdschr Geneeskd. 2010;154:A2282.

Abstract

Between 50% and 60% of patients with parkinsonism suffer from severe drooling (sialorrhoea). Sialorrhoea is a major social problem with medical risks as well, e.g. aspiration pneumonia. Sialorrhoea is not caused by increased production of saliva, but by impaired swallowing, leading to storage of saliva in the anterior part of the mouth. Sialorrhoea can be treated by anticholinergics, botulinum toxin injections, surgery and radiotherapy of the salivary glands. The optimal treatment of sialorrhoea needs to be determined individually, for which a decision tree is available.

摘要

50%至60%的帕金森病患者存在严重流涎(唾液分泌过多)问题。流涎不仅是一个主要的社会问题,还存在医疗风险,如吸入性肺炎。流涎并非由唾液分泌增加引起,而是吞咽功能受损导致唾液在口腔前部积聚所致。流涎可通过使用抗胆碱能药物、注射肉毒杆菌毒素、手术以及唾液腺放射治疗来进行治疗。流涎的最佳治疗方案需要因人而异来确定,为此有一个决策树可供参考。

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