乙醛酸对肝细胞硫酸根-草酸根交换体SAT-1（SLC26A1）表达的调节：肝脏与肾脏之间的代谢联系？ - Suppr

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Regulation of the expression of the hepatocellular sulfate-oxalate exchanger SAT-1 (SLC26A1) by glyoxylate: a metabolic link between liver and kidney?

作者信息

Stieger Bruno

出版信息

J Hepatol. 2011 Mar;54(3):406-7. doi: 10.1016/j.jhep.2010.09.011. Epub 2010 Oct 14.

DOI:10.1016/j.jhep.2010.09.011

PMID:21084130

Abstract

摘要

相似文献

Regulation of the expression of the hepatocellular sulfate-oxalate exchanger SAT-1 (SLC26A1) by glyoxylate: a metabolic link between liver and kidney?乙醛酸对肝细胞硫酸根-草酸根交换体SAT-1（SLC26A1）表达的调节：肝脏与肾脏之间的代谢联系？

J Hepatol. 2011 Mar;54(3):406-7. doi: 10.1016/j.jhep.2010.09.011. Epub 2010 Oct 14.

Glyoxylate is a substrate of the sulfate-oxalate exchanger, sat-1, and increases its expression in HepG2 cells.乙醛酸是硫酸盐-草酰乙酸交换体 sat-1 的底物，并增加其在 HepG2 细胞中的表达。

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The liver and kidney expression of sulfate anion transporter sat-1 in rats exhibits male-dominant gender differences.大鼠中硫酸根阴离子转运蛋白sat-1在肝脏和肾脏中的表达呈现出雄性主导的性别差异。

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Absence of the sulfate transporter SAT-1 has no impact on oxalate handling by mouse intestine and does not cause hyperoxaluria or hyperoxalemia.SAT-1 硫酸盐转运蛋白缺失对小鼠肠道草酸盐处理没有影响，也不会导致高草酸尿症或高草酸血症。

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