正常小鼠和营养不良小鼠肌肉中环磷酸鸟苷、1,6-二磷酸葡萄糖的水平以及磷酸果糖激酶的活性。
The levels of cyclic GMP and glucose 1,6-diphosphate, and the activity of phosphofructokinase, in muscle from normal and dystrophic mice.
作者信息
Beitner R, Haberman S, Nordenberg J, Cohen T J
出版信息
Biochim Biophys Acta. 1978 Sep 6;542(3):537-41. doi: 10.1016/0304-4165(78)90383-5.
PMID:210843
Abstract
A striking reduction in the levels of glucose 1,6-diphosphate and an increase in cyclic GMP were found in muscle from dystrophic mice. Concomitant to these changes, the allosteric activity of phosphofructokinase was found to be markedly reduced. These findings could offer an explanation for the observed reduction in glycolysis in the dystrophic muscle.
摘要
在营养不良小鼠的肌肉中发现，1,6 -二磷酸葡萄糖水平显著降低，环磷酸鸟苷水平升高。与这些变化同时出现的是，磷酸果糖激酶的变构活性明显降低。这些发现可以为营养不良肌肉中观察到的糖酵解减少现象提供一种解释。
Zotero 插件