Kumar Vinodh A, Knopp Edmond A, Zagzag David
Department of Diagnostic Radiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
J Comput Assist Tomogr. 2010 Nov-Dec;34(6):825-9. doi: 10.1097/RCT.0b013e3181ef77e2.
The purpose of this study was to compare the dynamic susceptibility-weighted contrast-enhanced (DSC) magnetic resonance (MR) perfusion and MR imaging findings between hemangioblastomas and pilocytic astrocytoma (PA).
We retrospectively identified 6 patients with hemangioblastomas and 8 patients with PAs who underwent MR imaging before resection. Using fluid-attenuated inversion-recovery imaging, we graded peritumoral edema as absent, minimal, mild, moderate, or severe. In addition, 3 patients with hemangioblastomas and 4 patients with PAs underwent DSC-MR imaging before resection.
We observed moderate to severe peritumoral edema in 6 patients with hemangioblastomas and none or minimal peritumoral edema in 8 patients with PAs. The mean relative cerebral blood volume was 7.7 (SD, 1.0) in patients with hemangioblastomas and 1.8 (SD, 1.8) in patients with PAs.
Our preliminary findings demonstrate significantly higher DSC-MR imaging relative cerebral blood volumes in patients with hemangioblastomas when compared with patients with PAs. In addition, moderate to severe peritumoral edema was associated with hemangioblastomas.
本研究旨在比较血管母细胞瘤与毛细胞型星形细胞瘤（PA）之间的动态磁敏感加权对比增强（DSC）磁共振（MR）灌注及MR成像表现。
我们回顾性纳入了6例血管母细胞瘤患者和8例PA患者，这些患者在切除术前均接受了MR成像检查。使用液体衰减反转恢复成像，我们将瘤周水肿分为无、轻度、中度或重度。此外，3例血管母细胞瘤患者和4例PA患者在切除术前接受了DSC-MR成像检查。
我们观察到6例血管母细胞瘤患者存在中度至重度瘤周水肿，而8例PA患者无或仅有轻度瘤周水肿。血管母细胞瘤患者的平均相对脑血容量为7.7（标准差，1.0），PA患者为1.8（标准差，1.8）。
我们的初步研究结果表明，与PA患者相比，血管母细胞瘤患者的DSC-MR成像相对脑血容量显著更高。此外，中度至重度瘤周水肿与血管母细胞瘤相关。
