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原发性骨淋巴瘤:表现为马尾综合征的多灶性疾病。

Primary bone lymphoma: polyostotic disease presenting as a cauda equina syndrome.

机构信息

Rehabilitation Division, Cruces Hospital, Barakaldo, Spain.

出版信息

J Clin Rheumatol. 2010 Dec;16(8):392-4. doi: 10.1097/RHU.0b013e3182005370.

Abstract

We report a patient with B-cell primary bone lymphoma with involvement of multiple vertebrae at presentation and rapid development of cauda equina syndrome. The patient presented subacute low-back pain, initially with good response to corticosteroid treatment.Primary bone lymphoma is a very unusual disease, commonly affecting only 1 vertebra. Despite this, our case involved multiple levels at the onset; furthermore, there were no adenopathies. Because of the information of the magnetic resonance imaging, an open biopsy of the vertebrae was performed for diagnosis. The reported cases of radicular syndromes secondary to a lymphoma as an initial symptom are extremely infrequently reported in the literature, above all for a B-cell lymphoma.

摘要

我们报告了一例以多发性脊椎受累和马尾综合征快速发展为特征的 B 细胞原发性骨淋巴瘤患者。该患者表现为亚急性下腰痛,最初对皮质类固醇治疗反应良好。原发性骨淋巴瘤是一种非常罕见的疾病,通常仅累及 1 个椎体。尽管如此,我们的病例在发病时累及多个水平;此外,没有淋巴结病。由于磁共振成像的信息,对脊椎进行了开放性活组织检查以明确诊断。文献中很少有报告称以神经根综合征为首发症状的淋巴瘤病例,尤其是 B 细胞淋巴瘤。

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