Batty J, Leavitt R A, Biondo N, Polin D
Museum of Natural History, University of Michigan, Ann Arbor 48109.
Arch Environ Contam Toxicol. 1990 Mar-Apr;19(2):283-90. doi: 10.1007/BF01056098.
White footed mice (Peromyscus leucopus) inhabiting an area surrounding a pond (Tyler) contaminated with polychlorinated biphenyls (PCBs) and metals (Cadmium, Zinc, Copper) had whole body burdens of 0.42-4.17 ppm PCBs (mean 2.3 ppm) and animals from a comparison nonpolluted site (WCC) had no detectable PCBs. Males and females caught at the polluted site in the winter months were not significantly different in body weight or length when compared to WCC animals, but Tyler animals had significantly increased relative liver, kidney, spleen and adrenal weights. In the summer months, mostly males were caught at both Tyler and WCC sites. Tyler males were significantly lighter than WCC males, and had a significantly increased relative liver weight when compared to the males from the WCC site. In addition, the adult Tyler males had significantly lower relative testis weights. At Tyler there was a significantly smaller proportion of juveniles and subadults in the population than at WCC. Polychlorinated biphenyls levels in the adult Tyler males were significantly positively correlated with relative liver weight, but there were no significant correlations with any of the other structures measured. These results suggest that at the polluted site there is inhibition of reproduction and changes in liver, spleen, adrenal, and testis function.
生活在一个被多氯联苯（PCBs）和金属（镉、锌、铜）污染的池塘（泰勒池塘）周边区域的白足鼠（白足鼠属）体内的多氯联苯全身负荷量为0.42 - 4.17 ppm（平均2.3 ppm），而来自对照无污染地点（WCC）的动物体内未检测到多氯联苯。与WCC地点的动物相比，冬季在污染地点捕获的雄性和雌性白足鼠在体重或体长上没有显著差异，但泰勒池塘的动物肝脏、肾脏、脾脏和肾上腺的相对重量显著增加。在夏季，泰勒池塘和WCC地点捕获的大多是雄性白足鼠。泰勒池塘的雄性白足鼠明显比WCC地点的雄性白足鼠轻，并且与WCC地点的雄性白足鼠相比，其肝脏相对重量显著增加。此外，成年泰勒池塘雄性白足鼠的睾丸相对重量明显较低。在泰勒池塘，种群中幼年和亚成年个体的比例明显低于WCC地点。成年泰勒池塘雄性白足鼠体内的多氯联苯水平与肝脏相对重量显著正相关，但与所测量的任何其他结构均无显著相关性。这些结果表明，在污染地点存在繁殖抑制以及肝脏、脾脏、肾上腺和睾丸功能的变化。
