Miklos G L, Cotsell J N
Molecular Neurobiology Group, Research School of Biological Sciences, Australian National University, Canberra.
Bioessays. 1990 Jan;12(1):1-6. doi: 10.1002/bies.950120102.
The chromocenter of Drosophila polytene chromosomes, which consists of two major chromatin types, has long been a troublesome region in molecular terms. The recent microcloning of part of this region, the isolation of a monoclonal antibody to a beta-heterochromatin binding protein, and new in situ studies now shed a little more light on this chromosomal region.
果蝇多线染色体的染色中心由两种主要染色质类型组成,长期以来在分子层面一直是个棘手的区域。最近对该区域部分片段的微克隆、针对一种β-异染色质结合蛋白的单克隆抗体的分离以及新的原位研究,现在对这个染色体区域有了更多的了解。