Govori Valbona, Humolli Isme, Cepreganov Metodi, Dedushaj Isuf, Gjikolli Bujar
University Department of Neurology, University Clinical Center, Kosovo.
Acta Clin Croat. 2010 Jun;49(2):133-8.
Brain tumors are a common cause of epilepsy. Tumor type and location are determining factors that significantly influence seizure frequency. The aim of this study was to analyze clinical data of patients diagnosed with brain tumors and epilepsy. Data for this study were obtained from patient medical records over a 6-year period (2000-2005). Patient history and findings obtained by diagnostic methods such as electroencephalography, computerized tomography and magnetic resonance were analyzed. Data were analyzed by appropriate statistical methods and the structure, prevalence, mean and standard deviation were calculated. The significance of results was tested by use of t-test and chi2-test. A total of 15 933 patient charts were analyzed. Out of 15 933 patients, 10.8% were diagnosed with epilepsy and 175 (1.09%) patients had brain tumor, 75 (42.86%) of which were significantly associated with epilepsy (P > 0.05). Almost forty-three percent (42.86%) of tumors were epileptogenic, with no significant sex difference (confidence level of 95%). Fifty-seven (32.5%) brain tumor patients were aged 51-60. The mean age of all patients with brain tumors was 41.6 years. Focal sensorimotor seizures were dominant in 40 (53.3%) cases. Among epilepsy cases with known etiology, 75 (6.8%) patients had epileptogenic tumors. Types of seizures in patients with epilepsy were different from seizures provoked by brain tumors. The most common tumor site was temporal region (43.4%). There was no significant difference according to epileptogenesis. Focal sensorimotor seizures were common in patients with frontal and parietal region tumors.
脑肿瘤是癫痫的常见病因。肿瘤类型和位置是显著影响癫痫发作频率的决定性因素。本研究的目的是分析被诊断为脑肿瘤和癫痫患者的临床数据。本研究的数据来自6年期间（2000 - 2005年）的患者病历。分析了通过脑电图、计算机断层扫描和磁共振成像等诊断方法获得的患者病史和检查结果。采用适当的统计方法对数据进行分析，并计算结构、患病率、均值和标准差。结果的显著性通过t检验和卡方检验进行检验。共分析了15933份患者病历。在15933名患者中，10.8%被诊断为癫痫，175名（1.09%）患者患有脑肿瘤，其中75名（42.86%）与癫痫显著相关（P>0.05）。几乎43%（42.86%）的肿瘤具有致痫性，无显著性别差异（95%置信水平）。57名（32.5%）脑肿瘤患者年龄在51 - 60岁之间。所有脑肿瘤患者的平均年龄为41.6岁。40例（53.3%）以局灶性感觉运动性发作为主。在病因已知的癫痫病例中，75名（6.8%）患者患有致痫性肿瘤。癫痫患者的发作类型与脑肿瘤诱发的发作不同。最常见的肿瘤部位是颞叶（43.4%）。根据致痫性无显著差异。额叶和顶叶肿瘤患者中局灶性感觉运动性发作很常见。
