Bidziński J, Bacia T, Trabka W
Kliniki Neurochirurgii Instytutu Chirurgii AM, Warszawie.
Pol Tyg Lek. 1994;49(4-5):110-2.
An incidence of tumors of the brain as a cause of drug-resistant epilepsy have been analysed. The analysis included patients operated for epilepsy at the Department of Neurosurgery, Medical Academy in Warsaw between 1987 and 1991. Malignant tumors were found in 21 out 85 patients (24.7%) treated surgically, 22.4% were benign tumors, and 52.9%--lesions of cicatricial character. The most frequent malignant tumor was fibrillary astrocytoma, noted in 57.1% of cases. Neurological examination has revealed discrete symptoms only in 2 out of 21 patients. CT scans have showed non-characteristic focus of decreased density in 12 patients (57.1%). Differentiation of tumor-produced epilepsy and those due to other focal lesions could not be made with the clinical course of seizures and EEG records. Actually, an incidence of tumors of the brain causing seizures refractory to pharmacologic treatment is increasing. Not characteristic clinical course and EEG records as well as CT scans are the main causes of delays in the surgery.
对作为耐药性癫痫病因的脑肿瘤发病率进行了分析。分析对象包括1987年至1991年期间在华沙医学院神经外科接受癫痫手术治疗的患者。在85例接受手术治疗的患者中,发现21例(24.7%)为恶性肿瘤,22.4%为良性肿瘤,52.9%为瘢痕性病变。最常见的恶性肿瘤是纤维性星形细胞瘤,占病例的57.1%。神经学检查仅在21例患者中的2例发现了轻微症状。CT扫描显示12例患者(57.1%)有密度降低的非特异性病灶。根据癫痫发作的临床过程和脑电图记录,无法区分肿瘤引起的癫痫和其他局灶性病变引起的癫痫。实际上,导致药物治疗难治性癫痫发作的脑肿瘤发病率正在上升。不典型的临床过程、脑电图记录以及CT扫描是手术延迟的主要原因。