Schulmeister Lisa
J Support Oncol. 2010 Sep-Oct;8(5):212-5. doi: 10.1016/j.suponc.2010.09.002.
Although vesicant chemotherapy extravasations cannot be entirely prevented, the risk of extravasation can be reduced by adhering to guidelines for safe vesicant administration. These include engaging patients in extravasation-prevention efforts, thoroughly assessing patients receiving vesicants, selecting an appropriate administration site for peripheral vesicant administration, and checking for a blood return prior to and during vesicant administration. In addition, whenever an extravasation occurs or is suspected, vesicant administration must immediately cease, and the appropriate antidote or treatment needs to be promptly administered.
虽然刺激性化疗药物外渗无法完全避免，但遵循刺激性药物安全给药指南可降低外渗风险。这些措施包括让患者参与外渗预防工作、全面评估接受刺激性药物治疗的患者、为外周注射刺激性药物选择合适的给药部位，以及在给药前和给药期间检查回血情况。此外，一旦发生或怀疑发生外渗，必须立即停止刺激性药物给药，并及时给予适当的解毒剂或治疗。
