Park Young Gyu, Kim Jong-Yeup, Yang Dong Won, Lee Seungtaek, Park Poomin, Choi Jong Gwon
Department of Oncology-Hematology, Konyang University Hospital, Daejeon, Republic of Korea.
Department of Biomedical Informatics, College of Medicine, Konyang University, Daejeon, Republic of Korea.
Med Devices (Auckl). 2025 May 2;18:271-280. doi: 10.2147/MDER.S495996. eCollection 2025.
An infusion pump designed to deliver a specific volume at a predetermined rate is unable to detect extravasation and may continue infusion despite increased tissue resistance caused by extravasation. Consequently, it is recommended that vesicant drugs, such as chemotherapeutic agents, be administered via gravity infusion to reduce the risk of tissue damage. However, intravenous flow regulators used for gravity infusion have limitations because the infusion rate is influenced by the height, venous pressure, and viscosity of the fluid, which can change with temperature. In this study, we measured the accuracy of Accudrip, a new gravity-based automatic infusion control device designed to correct fluctuating infusion rates.
In 59 cancer patients administered with anticancer drugs, the actual administration rate using Accudrip under various administration conditions and the theoretical administration rate were measured and analyzed 100 times.
Comparing the theoretical and actual administration rates using Accudrip confirmed that it can be injected with an average error rate of 4.75%, which clinically demonstrated sufficient accuracy for fluid administration.
The gravity-based automatic infusion system showed high accuracy consistent with the theoretical rate of administration even under multiple infusion conditions of cancer patients with chemoport. This system (Accudrip) will greatly contribute to accurate drug administration and minimization of adverse events in real-world hospital settings.
一种旨在以预定速率输送特定体积液体的输液泵无法检测到渗漏，并且尽管渗漏导致组织阻力增加，仍可能继续输液。因此，建议通过重力输注来给予诸如化疗药物等具有刺激性的药物，以降低组织损伤的风险。然而，用于重力输注的静脉输液调节器存在局限性，因为输液速率受液体高度、静脉压力和粘度的影响，而这些因素会随温度变化。在本研究中，我们测量了Accudrip（一种旨在纠正波动输液速率的新型基于重力的自动输液控制装置）的准确性。
在59例接受抗癌药物治疗的癌症患者中，在各种给药条件下使用Accudrip测量并分析实际给药速率和理论给药速率100次。
比较使用Accudrip的理论给药速率和实际给药速率证实，其平均误差率为4.75%，这在临床上证明了其在液体给药方面具有足够的准确性。
即使在带化疗端口的癌症患者的多种输液条件下，基于重力的自动输液系统也显示出与理论给药速率一致的高精度。该系统（Accudrip）将极大地有助于在实际医院环境中实现准确给药并将不良事件降至最低。
