Lemoine Tara J, Kaza Aditya K, Gray Robert, Day Ronald W, Tani Lloyd Y, Poss William Bradley
Division of Pediatric Critical Care, University of Utah School of Medicine, Salt Lake City, UT 84113, USA.
Congenit Heart Dis. 2010 Sep-Oct;5(5):462-4. doi: 10.1111/j.1747-0803.2010.00386.x.
Alagille syndrome is a dominantly inherited multisystem disorder involving multiple organs including the liver, heart, eyes, face, and skeleton. Congenital heart defects, the majority of which are right-sided, contribute significantly to the mortality of these patients. We report a patient with Alagille syndrome who presented with mitral valve regurgitation requiring valvuloplasty and subsequent mitral valve replacement. The patient was ultimately diagnosed with anomalous origin of the left coronary artery from the pulmonary artery and underwent successful reimplantation.
阿拉吉列综合征是一种常染色体显性遗传的多系统疾病，累及包括肝脏、心脏、眼睛、面部和骨骼在内的多个器官。先天性心脏缺陷在这些患者中占大多数，主要为右侧心脏缺陷，是导致这些患者死亡的重要原因。我们报告一名患有阿拉吉列综合征的患者，该患者出现二尖瓣反流，需要进行瓣膜成形术，随后进行二尖瓣置换术。该患者最终被诊断为左冠状动脉起源于肺动脉异常，并成功接受了冠状动脉再植术。
