Service de neurologie, hôpital Avicenne, AP-HP, 125, route de Stalingrad, 93009 Bobigny, France.
Rev Neurol (Paris). 2011 Feb;167(2):177-80. doi: 10.1016/j.neurol.2010.07.020. Epub 2010 Nov 17.
Wallenberg's syndrome and ipsilateral paresis due to combined infarction of the lateral medullary and cervical spinal infarction is known as Opalski syndrome. This rarely described syndrome was reported, to our knowledge, with DWI MRI, only once.
We report the case of a 43-year-old man with autosomal dominant polycystic kidney disease who, after a brief episode of coma, developed Wallenberg syndrome and ipsilateral hemiparesis. Initial diffusion weighted-imaging MRI showed a high-intensity signal involving the lateral medulla oblongata and the spinal cord; but FLAIR MRI sequences showed bilateral high-intensity signals in the lateral medulla oblongata and spinal cord and high-intensity signals in the right and left cerebellar hemisphere in the PICA territories. MRI performed one year later showed an infarction involving the left medullary area and adjacent spinal segments alone.
This observation illustrates a rare syndrome of lateral medullary infarction, associated with spinal cord infarction related to a possible transient basilar occlusion.
延髓外侧和颈髓同时梗死导致的 Wallenberg 综合征和同侧偏瘫,被称为 Opalski 综合征。据我们所知,这种很少被描述的综合征仅在一次弥散加权 MRI 报告中被报道过。
我们报告了一例 43 岁的常染色体显性多囊肾病患者,他在短暂昏迷后出现 Wallenberg 综合征和同侧偏瘫。初始弥散加权成像 MRI 显示延髓外侧和脊髓高信号;但 FLAIR MRI 序列显示延髓外侧和脊髓双侧高信号,右侧和左侧小脑后下动脉区域的左小脑半球高信号。一年后进行的 MRI 显示仅左侧延髓区域和相邻脊髓节段的梗死。
这种观察结果说明了一种罕见的延髓外侧梗死综合征,伴有可能与短暂基底动脉闭塞相关的脊髓梗死。