Vemavarapu Lakshmi, Alatassi Houda, Moghadamfalahi Mana
University of Louisville, Louilville, KY 40202, USA.
Int J Surg Pathol. 2011 Feb;19(1):120-2. doi: 10.1177/1066896910387601. Epub 2010 Nov 17.
Transitional cell tumors of the ovary comprise about 1% to 2% of all ovarian neoplasms. Most of these tumors are benign Brenner tumors and account for about 5% of benign surface epithelial-stromal tumors. Spicules of calcifications are found in the stroma of about 50% of benign Brenner tumors. Although diagnostic challenges might occur more frequently with either of the borderline or malignant Brenner tumors, this problem is not that common when diagnosing a benign Brenner tumor. This study reports a case of benign Brenner tumor with exuberant dystrophic calcifications that obscured most of the epithelium and posed a diagnostic challenge in differentiating it from the more common malignant counterparts such as serous carcinoma and specifically psammocarcinoma.
卵巢移行细胞肿瘤约占所有卵巢肿瘤的1%至2%。这些肿瘤大多为良性勃勒纳瘤，约占良性表面上皮-间质肿瘤的5%。约50%的良性勃勒纳瘤间质中可见钙化小体。虽然交界性或恶性勃勒纳瘤可能更常出现诊断难题，但在诊断良性勃勒纳瘤时，这个问题并不常见。本研究报告了一例良性勃勒纳瘤伴有大量营养不良性钙化，钙化掩盖了大部分上皮，在将其与更常见的恶性肿瘤如浆液性癌尤其是砂粒体癌鉴别时带来了诊断挑战。
