Coskun Ozlem, Comlekci Selcuk
Department of Biomedical Device Technology, Süleyman Demirel University, Isparta, Turkey.
Toxicol Ind Health. 2011 May;27(4):329-33. doi: 10.1177/0748233710387005. Epub 2010 Nov 18.
The present study has investigated the potential effects of extremely low frequency (ELF) electric field exposure on plasma cholesterol and triglyceride levels of adult male rats. Sixty rats have been divided into three independent groups randomly, 20 of which arranged as controls (without exposure to 50 Hz electric field), 20 of which have been exposed to a 50 Hz electric field for 10 days and 20 of which have been exposed to a 50-Hz electric field for 30 days. Levels of total cholesterol and triglyceride in plasma samples have been measured. Total cholesterol concentration of the plasma in group 2 with short-term exposure and group 3 with long-term exposure to 50 Hz EF (65.33 ± 15.31 mg/dL and 59.55 ± 15.01 mg/dL, respectively) has showed significant decrease when compared with control groups (70.44 ± 19.60 mg/dL). Also, plasma triglyceride showed similar changes (control: 84.44 ± 16.79 mg/dL, 67.33 ± 15.63 and 51.53 ± 14.17 mg/dL in group 1 and 2, respectively). Fifty Hz electric field may decrease plasma total cholesterol and triglyceride levels in rodents significantly, especially with long-term exposure.
本研究调查了极低频（ELF）电场暴露对成年雄性大鼠血浆胆固醇和甘油三酯水平的潜在影响。60只大鼠被随机分为三个独立组，其中20只作为对照组（不暴露于50Hz电场），20只暴露于50Hz电场10天，20只暴露于50Hz电场30天。测量了血浆样本中总胆固醇和甘油三酯的水平。与对照组（70.44±19.60mg/dL）相比，短期暴露的第2组和长期暴露的第3组血浆中总胆固醇浓度（分别为65.33±15.31mg/dL和59.55±15.01mg/dL）显著降低。此外，血浆甘油三酯也有类似变化（对照组：84.44±16.79mg/dL；第1组和第2组分别为67.33±15.63和51.53±14.17mg/dL）。50Hz电场可能会显著降低啮齿动物血浆总胆固醇和甘油三酯水平，尤其是长期暴露时。
