Los Angeles, Calif. From Children's Hospital Los Angeles.
Plast Reconstr Surg. 2011 Mar;127(3):1263-1269. doi: 10.1097/PRS.0b013e318205f3ac.
The purpose of this study was to compare the efficacy of presurgical nasoalveolar molding in treating unilateral versus bilateral cleft lip–cleft palate patients.
A blinded, retrospective study was conducted with 16 unilateral and 13 bilateral cleft lip–cleft palate patients. Pretreatment and posttreatment facial and intraoral impressions were used to compare soft- and hard-tissue changes.
Nasoalveolar molding therapy improves nasal angle in unilateral (p = 0.010) and bilateral cleft lip–cleft palate (p = 0.001) patients, and improves nostril width in unilateral (p = 0.005) and bilateral cleft lip–cleft palate (p = 0.028) patients. Treatment significantly improves nostril breadth only in unilateral cleft lip–cleft palate patients (p = 0.005). Compared with bilateral cleft lip–cleft palate patients, unilaterally affected patients were more asymmetric before and after nasoalveolar molding therapy. Nasoalveolar molding more effectively increases columellar height (p = 0.002) and columellar width (p = 0.002) in the bilateral cleft lip–cleft palate group. Although starting bialar widths did not significantly differ between the two groups, nasoalveolar molding significantly decreased bialar width only in unilateral cleft lip–cleft palate patients (p = 0.032). When the intersegment alveolar cleft distances of the bilateral cleft lip–cleft palate patients were summed, an improvement similar to that in unilateral cleft lip–cleft palate patients was observed. Furthermore, nasoalveolar molding appeared to prevent alveolar width widening as patients continued to grow.
There are differences in efficacy between unilateral and bilateral cleft lip–cleft palate patients undergoing nasoalveolar molding. Understanding these differences may help physicians and dentists better shape expectations.
本研究旨在比较术前鼻牙槽塑形治疗单侧和双侧唇腭裂患者的疗效。
对 16 例单侧和 13 例双侧唇腭裂患者进行了一项盲法、回顾性研究。使用术前和术后的面部和口腔印模来比较软组织和硬组织的变化。
鼻牙槽塑形治疗可改善单侧(p=0.010)和双侧唇腭裂患者的鼻角(p=0.001),并改善单侧(p=0.005)和双侧唇腭裂患者的鼻孔宽度(p=0.028)。治疗仅在单侧唇腭裂患者中显著改善鼻孔宽度(p=0.005)。与双侧唇腭裂患者相比,接受鼻牙槽塑形治疗前和治疗后,单侧受累患者的不对称性更为明显。鼻牙槽塑形更有效地增加了双侧唇腭裂患者的鼻中隔高度(p=0.002)和鼻中隔宽度(p=0.002)。尽管两组患者的起始双侧宽度没有显著差异,但鼻牙槽塑形仅在单侧唇腭裂患者中显著减小了双侧宽度(p=0.032)。当对双侧唇腭裂患者的牙槽裂间距离进行总和时,观察到与单侧唇腭裂患者相似的改善。此外,鼻牙槽塑形似乎可以防止牙槽宽度随着患者的生长而变宽。
接受鼻牙槽塑形治疗的单侧和双侧唇腭裂患者的疗效存在差异。了解这些差异可以帮助医生和牙医更好地调整期望。