Centre of Arrhythmia Diagnosis and Treatment, Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Clin Cardiol. 2010 Nov;33(11):715-9. doi: 10.1002/clc.20808.
Paced QRS duration, a good marker of ventricular asynchrony while pacing, has been accepted as a valuable predictor of new-onset heart failure in patients receiving right ventricular apical pacing. But nowadays we have little evidence for predicting paced QRS duration before the implantation.
There might be relationships between paced QRS duration and demographic characteristics, clinical features such as comorbidities, native QRS duration, or preimplant cardiac size. The purpose of this article was to identify potential predictors of paced QRS duration in patients receiving right ventricular apical pacing for complete atrioventricular block.
One hundred seventy patients with right ventricular apical pacing for complete atrioventricular block were divided into 2 groups according to whether the paced QRS duration was longer than 170 ms or not. Demographic characteristics, clinical features, electrocardiogram and echocardiography before implantation, and electrocardiogram immediately after implantation, were retrospectively recorded.
Preimplant left ventricular end-diastolic dimension (LVEDD) and body weight were found to be independently associated with the paced QRS duration. Although both of them had low sensitivity and specificity in predicting paced QRS duration longer than 170 ms, the specificity could increase to 81.2% when they were combined.
Both preimplant LVEDD and body weight independently associate with paced QRS duration in patients receiving apical pacing for complete atrioventricular block. Although whether they really have an effect on new-onset heart failure still needs to be verified, and these findings might be a good indication.
起搏 QRS 时限是起搏时心室失同步的良好标志物,已被接受为接受右心室心尖部起搏的患者新发心力衰竭的有价值预测指标。但目前我们在植入前预测起搏 QRS 时限的证据很少。
起搏 QRS 时限与人口统计学特征、合并症等临床特征、固有 QRS 时限或植入前心脏大小之间可能存在关系。本文的目的是确定接受右心室心尖部起搏治疗完全性房室传导阻滞的患者起搏 QRS 时限的潜在预测因子。
根据起搏 QRS 时限是否大于 170 ms,将 170 例接受右心室心尖部起搏治疗完全性房室传导阻滞的患者分为 2 组。回顾性记录植入前的人口统计学特征、临床特征、心电图和超声心动图以及植入后即刻的心电图。
植入前左心室舒张末期内径(LVEDD)和体重被发现与起搏 QRS 时限独立相关。尽管它们在预测起搏 QRS 时限大于 170 ms 时的敏感性和特异性均较低,但当两者结合时,特异性可提高至 81.2%。
在接受完全性房室传导阻滞心尖部起搏的患者中,植入前 LVEDD 和体重均与起搏 QRS 时限独立相关。尽管它们是否真的对新发心力衰竭有影响仍需验证,但这些发现可能是一个很好的指标。