Copt C, Christodoulou M, Friolet R, Berclaz R, Bettschart V, Troillet N
Service des maladies infectieuses, Institut central des hôpitaux valaisans, Sion.
Rev Med Suisse. 2010 Oct 13;6(266):1910-3.
Secondary to severe hospital outbreaks due to hypervirulent strains of Clostridium difficile, several surveillance systems in North-America and Europe observed an increase in infections due to this micro-organism, also in the outpatient setting. The case reported in the present article illustrates the fulminant presentation that a C. difficile colitis can show in a previously healthy person without prior contact with healthcare facilities. It introduces a review of some recent publications on the current changes in the epidemiology, clinical presentation, diagnosis and treatment of this disease.
由于高毒力艰难梭菌菌株导致医院严重暴发,北美和欧洲的多个监测系统发现,这种微生物引起的感染有所增加,在门诊环境中也是如此。本文报告的病例说明了艰难梭菌结肠炎在既往健康、未曾接触过医疗机构的人身上可能出现的暴发性表现。本文还对近期一些关于该疾病流行病学、临床表现、诊断和治疗方面当前变化的出版物进行了综述。