Liu Fei, Wang Xin, Bai Jing
Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Oct;27(5):1152-7.
As a recently emerging molecular imaging technique, fluorescent molecular imaging has the advantage of fast imaging, simple operation, high sensitivity, low cost, nonionizing radiation and so on. Through the real-time, non-invasive, specific tracking and detection of tumorigenesis, metastases, angiogenesis, and the therapeutic response to antitumor drugs in vivo, we can study the physiological and pathological processes within tumors at cellular and molecular levels. Fluorescent molecular imaging provides effective methods for the early detection and targeted therapy of tumor, for the intraoperative visualization of tumor foci, as well as for the development of new antitumor drugs in the future clinical practice.
作为一种新兴的分子成像技术，荧光分子成像具有成像速度快、操作简单、灵敏度高、成本低、无电离辐射等优点。通过对肿瘤发生、转移、血管生成以及体内抗肿瘤药物治疗反应进行实时、无创、特异性追踪和检测，我们能够在细胞和分子水平上研究肿瘤内部的生理和病理过程。荧光分子成像为肿瘤的早期检测和靶向治疗、术中肿瘤病灶可视化以及未来临床实践中新型抗肿瘤药物的研发提供了有效的方法。
