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胆汁酸转运蛋白的现代研究方法。

Modern approaches to bile acid transport proteins.

作者信息

Wilson F A

机构信息

Pennsylvania State University College of Medicine.

出版信息

Hosp Pract (Off Ed). 1990 Apr 15;25(4):95-9, 104-8, 110. doi: 10.1080/21548331.1990.11703937.

Abstract

New techniques for studying solute uptake across epithelial membranes in the gut are providing a clearer picture of bile acid handling. In the small intestine, liver, and other sites, membrane proteins that mediate active bile acid transport are key players. Better understanding of these transporters may lead to elucidation of disorders of bile handling and better treatment of such disorders.

摘要

研究肠道上皮细胞膜溶质摄取的新技术,正为胆汁酸处理提供更清晰的图景。在小肠、肝脏和其他部位,介导胆汁酸主动转运的膜蛋白起着关键作用。对这些转运蛋白的深入了解,可能有助于阐明胆汁处理紊乱的机制,并更好地治疗此类疾病。

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