Brisson-Lougarre A, Blum C, Bayard F
C R Seances Soc Biol Fil. 1978;172(2):355-8.
The present preliminary data obtained from intact fibroblasts of adult mice (polyploid stem L 929) suggest that this cell system possesses high-affinity and saturable nuclear binding sites for triiodothyronine. As estimated by the Scatchard analysis, the equilibrium dissociation constant is approximately 2 X 10(-10) moles, the maximal binding capacity is about 2 000 sites for T3 per cell nucleus.
从成年小鼠(多倍体干细胞L 929)完整的成纤维细胞获得的目前初步数据表明,该细胞系统具有三碘甲状腺原氨酸的高亲和力和可饱和核结合位点。通过Scatchard分析估计,平衡解离常数约为2×10(-10)摩尔,每个细胞核T3的最大结合容量约为2000个位点。