Kaplan Norman M
University of Texas Southwestern Medical Center at Dallas, TX 75390-8586, USA.
Expert Rev Cardiovasc Ther. 2010 Nov;8(11):1527-30. doi: 10.1586/erc.10.135.
Primary aldosteronism is more common than previously recognized but much less common than most experts in this arena have recently stated. The recognition of autonomous hyperaldosteronism is not difficult but the identification of the source of excess aldosterone requires a costly and difficult procedure. Most patients with hyperaldosteronism turn out to have bilateral adrenal hyperplasia for which medical therapy with an aldosterone blocker is indicated. Many of these patients are not hypokalemic and can safely be treated without the need for a costly and usually negative work-up.
原发性醛固酮增多症比之前认为的更为常见，但比该领域大多数专家最近所说的要少见得多。自主性醛固酮增多症的诊断并不困难，但确定醛固酮过量的来源需要一个昂贵且困难的过程。大多数醛固酮增多症患者最终被发现患有双侧肾上腺增生，对此需使用醛固酮阻滞剂进行药物治疗。这些患者中的许多人并无低钾血症，无需进行昂贵且通常为阴性结果的检查即可安全治疗。
