Stabouli Stella, Papakatsika Sofia, Kotsis Vasilios
Pediatric Intensive Care Unit, Hippokration Hospital, Thessaloniki, Greece.
Expert Rev Cardiovasc Ther. 2010 Nov;8(11):1559-65. doi: 10.1586/erc.10.141.
Hypothyroidism has been recognized as a cause of secondary hypertension. Previous studies on the prevalence of hypertension in subjects with hypothyroidism have demonstrated elevated blood pressure values. Increased peripheral vascular resistance and low cardiac output has been suggested to be the possible link between hypothyroidism and diastolic hypertension. The hypothyroid population is characterized by significant volume changes, initiating a volume-dependent, low plasma renin activity mechanism of blood pressure elevation. This article summarizes previous studies on the impact of hypothyroidism on blood pressure and early atherosclerotic process.
甲状腺功能减退已被确认为继发性高血压的一个病因。先前关于甲状腺功能减退患者高血压患病率的研究表明血压值升高。外周血管阻力增加和心输出量降低被认为可能是甲状腺功能减退与舒张期高血压之间的联系。甲状腺功能减退人群的特点是有显著的容量变化，启动了一种依赖容量的、血浆肾素活性低的血压升高机制。本文总结了先前关于甲状腺功能减退对血压和早期动脉粥样硬化进程影响的研究。
