Heidary Gena, Rizzo Joseph F
Neuro-Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.
Semin Ophthalmol. 2010 Sep-Nov;25(5-6):198-205. doi: 10.3109/08820538.2010.518462.
Idiopathic intracranial hypertension (IIH), or pseudotumor cerebri, describes a condition of elevated intracranial pressure (ICP) that typically presents in obese women of childbearing age with symptoms and signs of posture-dependent headaches, pulsatile tinnitus, visual changes, and papilledema. Optical coherence tomography (OCT) has begun to be utilized as an adjunctive, quantitative tool in the evaluation of patients with IIH to help distinguish between true optic nerve head edema and pseudopapilledema, and to contribute to our understanding of the consequences of prolonged optic nerve edema. Although few longitudinal studies of patients with IIH have been published to date, it appears that there may be a correlation between retinal nerve fiber layer (RNFL) thickness and visual function. With the new spectral domain OCT, additional parameters of the optic nerve imaging, including volume and height measurements, might provide greater sensitivity of the response to treatment and the long-term visual outcome in patients with IIH.
特发性颅内高压（IIH），即假性脑瘤，描述的是一种颅内压（ICP）升高的病症，通常见于育龄肥胖女性，伴有体位性头痛、搏动性耳鸣、视力变化和视乳头水肿等症状和体征。光学相干断层扫描（OCT）已开始被用作评估IIH患者的辅助定量工具，以帮助区分真正的视神经乳头水肿和假性视乳头水肿，并有助于我们了解视神经长期水肿的后果。尽管迄今为止很少有关于IIH患者的纵向研究发表，但视网膜神经纤维层（RNFL）厚度与视觉功能之间似乎可能存在关联。使用新的光谱域OCT，视神经成像的其他参数，包括体积和高度测量，可能会为IIH患者对治疗的反应及长期视觉结果提供更高的敏感性。
