He Ming, Cestari Dean, Cunnane Mary Beth, Rizzo Joseph F
Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA.
Semin Ophthalmol. 2010 Sep-Nov;25(5-6):225-32. doi: 10.3109/08820538.2010.518450.
Ischemic optic neuropathy and optic neuritis are the most common causes of unilateral non-glaucomatous visual loss. While they have distinctive clinical features, they also share some overlapping profiles that make it difficult to clinically distinguish these two entities. MRI with gadolinium has been proven to be helpful to confirm the diagnosis of optic neuritis, but ischemic optic neuropathy remains a clinical diagnosis. Diffusion MRI, a newly advanced technique, has been used in studying the pathophysiology of optic neuritis, but its use in ischemic optic neuropathy is limited. Diffuse MRI may potentially be of help to diagnose ischemic optic neuropathy.
缺血性视神经病变和视神经炎是单侧非青光眼性视力丧失的最常见原因。虽然它们有独特的临床特征，但也有一些重叠的表现，这使得在临床上难以区分这两种情况。钆增强磁共振成像已被证明有助于确诊视神经炎，但缺血性视神经病变仍然是一种临床诊断。扩散磁共振成像作为一种新的先进技术，已被用于研究视神经炎的病理生理学，但其在缺血性视神经病变中的应用有限。扩散磁共振成像可能有助于诊断缺血性视神经病变。
