Bahrani Hasan M, Fazelat Ahad A, Thomas Mathis, Hirose Tatsuo, Kroll Arnold J, Lou Peter L, Ryan Edward A
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.
Semin Ophthalmol. 2010 Sep-Nov;25(5-6):275-82. doi: 10.3109/08820538.2010.518109.
The goal of this study was to review, evaluate, and perform a meta-analysis on the current literature that reports rates of postoperative endophthalmitis after small gauge transconjunctival sutureless vitrectomy (TSV) and compare it to 20-gauge pars plana vitrectomy (20G PPV).
We performed an extensive review of the current literature. We included only large comparative institutional reviews. Meta-analysis of these reviews was performed.
We found six large retrospective comparative cases series on the 25-gauge (25G) TSV as compared to 20G PPV. The test for homogeneity for the meta-analysis indicates that the studies are not homogeneous and therefore the evidence is tentative.
We cannot conclude that 25G TSV has a higher rate of postoperative endophthalmitis compared to the 20G PPV. Future retrospective or prospective trials need to take into consideration multiple factors.
本研究的目的是对目前报告小切口经结膜无缝合玻璃体切除术(TSV)术后眼内炎发生率的文献进行综述、评估并进行荟萃分析,并将其与20G标准三通道玻璃体切除术(20G PPV)进行比较。
我们对当前文献进行了广泛的综述。我们仅纳入大型比较性机构综述。对这些综述进行了荟萃分析。
我们发现了6个关于25G TSV与20G PPV对比的大型回顾性比较病例系列。荟萃分析的同质性检验表明这些研究并非同质,因此证据是初步的。
我们不能得出25G TSV术后眼内炎发生率高于20G PPV的结论。未来的回顾性或前瞻性试验需要考虑多个因素。