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吞咽困难患者的营养支持:治疗方法、风险及并发症

Nutritional support of the dysphagic patient: methods, risks, and complications of therapy.

作者信息

Sitzmann J V

机构信息

Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.

出版信息

JPEN J Parenter Enteral Nutr. 1990 Jan-Feb;14(1):60-3. doi: 10.1177/014860719001400160.

Abstract

The indications, methods, and complications of nutritional support of 90 patients admitted with a primary complaint of dysphagia were reviewed. Patients were divided into two groups based on etiology of dysphagia (central neurologic vs local mechanical dysfunction). All patients on admission exhibited marked malnutrition with an average weight loss of 12 +/- 9.8% body weight, serum transferrin 165 +/- 60.1 mg/dl, and albumin 3.2 +/- 0.85 mg/dl. All patients were placed on either enteral (63%) or parenteral (37%) nutrition. Twenty-seven percent of all patients suffered a complication of nutritional therapy. Patients with nasoenteric tubes had a 10% complication incidence (aspiration or endotracheal placement of tube) resulting in a 30% mortality rate; significantly higher (p less than 0.05) than seen with other modalities. Any form of upper enteric feeding (nasoenteric or gastrostomy) was associated with significantly increased (p less than 0.01) risk of aspiration pneumonia. It is concluded that patients admitted to hospital with dysphagia as the major complaint suffer from severe malnutrition, and that upper gastrointestinal intubation should not be employed for feeding until the dysphagia has resolved.

摘要

回顾了90例以吞咽困难为主诉入院患者的营养支持指征、方法及并发症。根据吞咽困难的病因(中枢神经功能障碍与局部机械性功能障碍)将患者分为两组。所有患者入院时均表现出明显营养不良,平均体重减轻12±9.8%,血清转铁蛋白165±60.1mg/dl,白蛋白3.2±0.85mg/dl。所有患者均接受肠内营养(63%)或肠外营养(37%)。27%的患者发生了营养治疗并发症。鼻肠管患者的并发症发生率为10%(误吸或导管置入气管),死亡率为30%;显著高于(p<0.05)其他方式。任何形式的上消化道喂养(鼻肠管或胃造口术)均与吸入性肺炎风险显著增加(p<0.01)相关。结论是以吞咽困难为主诉入院的患者存在严重营养不良,在吞咽困难缓解之前不应采用上消化道插管进行喂养。

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